Why Protocol Design Determines the Success of Early-Stage Clinical Trials Executive Summary A significant proportion of early-stage clinical trials fail because the trial was incorrectly designed. Across academia, biotech and pharmaceuticals, as well as investigator-initiated studies, protocol design is a crucial pillar of the study and cannot be treated as an administrative prerequisite. Otherwise, studies suffer from predictable and preventable issues including: Uninterpret

Our latest blog post explores split-face studies, what they are, when to use them, and how to get them right.